Browsing by Author "Berg, Philipp"

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    Evolutionary Pathlines for Blood Flow Exploration in Cerebral Aneurysms
    (The Eurographics Association, 2019) Behrendt, Benjamin; Engelke, Wito; Berg, Philipp; Beuing, Oliver; Preim, Bernhard; Hotz, Ingrid; Saalfeld, Sylvia; Kozlíková, Barbora and Linsen, Lars and Vázquez, Pere-Pau and Lawonn, Kai and Raidou, Renata Georgia
    Blood flow simulations play an important role for the understanding of vascular diseases, such as aneurysms. However, analysis of the resulting flow patterns, especially comparisons across patient groups, are challenging. Typically, the hemodynamic analysis relies on trial and error inspection of the flow data based on pathline visualizations and surface renderings. Visualizing too many pathlines at once may obstruct interesting features, e.g., embedded vortices, whereas with too little pathlines, particularities such as flow characteristics in aneurysm blebs might be missed. While filtering and clustering techniques support this task, they require the pre-computation of pathlines densely sampled in the space-time domain. Not only does this become prohibitively expensive for large patient groups, but the results often suffer from undersampling artifacts. In this work, we propose the usage of evolutionary algorithms to reduce the overhead of computing pathlines that do not contribute to the analysis, while simultaneously reducing the undersampling artifacts. Integrated in an interactive framework, it efficiently supports the evaluation of hemodynamics for clinical research and treatment planning in case of cerebral aneurysms. The specification of general optimization criteria for entire patient groups allows the blood flow data to be batch-processed. We present clinical cases to demonstrate the benefits of our approach especially in presence of aneurysm blebs. Furthermore, we conducted an evaluation with four expert neuroradiologists. As a result, we report advantages of our method for treatment planning to underpin its clinical potential.
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    Visual Exploration of Intracranial Aneurysm Blood Flow Adapted to the Clinical Researcher
    (The Eurographics Association, 2021) Behrendt, Benjamin; Engelke, Wito; Berg, Philipp; Beuing, Oliver; Hotz, Ingrid; Preim, Bernhard; Saalfeld, Sylvia; Oeltze-Jafra, Steffen and Raidou, Renata Georgia
    Rupture risk assessment is a key to devise patient-specific treatment plans of cerebral aneurysms. To understand and predict the development of aneurysms and other vascular diseases over time, both hemodynamic flow patterns and their effect on the vessel surface need to be analyzed. Flow structures close to the vessel wall often correlate directly with local changes in surface parameters, such as pressure or wall shear stress. However, especially for the identification of specific blood flow characteristics that cause local startling parameters on the vessel surface, like elevated pressure values, an interactive analysis tool is missing. In order to find meaningful structures in the entirety of the flow, the data has to be filtered based on the respective explorative aim. Thus, we present a combination of visualization, filtering and interaction techniques for explorative analysis of blood flow with a focus on the relation of local surface parameters and underlying flow structures. In combination with a filtering-based approach, we propose the usage of evolutionary algorithms to reduce the overhead of computing pathlines that do not contribute to the analysis, while simultaneously reducing the undersampling artifacts. We present clinical cases to demonstrate the benefits of both our filter-based and evolutionary approach and showcase its potential for patient-specific treatment plans.