MOBS - Multi-Omics Brush for Subgraph Visualisation

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dc.contributor.authorHeylen, Driesen_US
dc.contributor.authorPeeters, Jannesen_US
dc.contributor.authorErtaylan, Gökhanen_US
dc.contributor.authorHooyberghs, Jefen_US
dc.contributor.authorAerts, Janen_US
dc.contributor.editorKrone, Michaelen_US
dc.contributor.editorLenti, Simoneen_US
dc.contributor.editorSchmidt, Johannaen_US
dc.date.accessioned2022-06-02T15:29:07Z
dc.date.available2022-06-02T15:29:07Z
dc.date.issued2022
dc.description.abstractOne of the big opportunities in multi-omics analysis is the identification of interactions between molecular entities and their association with diseases. In analyzing and expressing these interactions in the search for new hypotheses, multi-omics data is often either translated into matrices containing pairwise correlations and distances, or visualized as node-link diagrams. A major problem when visualizing large networks however is the occurrence of hairball-like graphs, from which little to none information can be extracted. It is of interest to investigate subgroups of markers that are closely associated with each other, rather than just looking at the overload of all interactions. Hence, we propose MOBS (Multi-Omics Brush for Subgraph visualisation), a web-based visualisation interface that can provide both an overview and detailed views on the data. By means of a two dimensional brush on a heatmap that includes hierarchical clustering, relationships of interest can be extracted from a fully connected graph, to enable detailed analysis of the subgraph of interest.en_US
dc.description.sectionheadersPosters
dc.description.seriesinformationEuroVis 2022 - Posters
dc.identifier.doi10.2312/evp.20221116
dc.identifier.isbn978-3-03868-185-4
dc.identifier.pages43-45
dc.identifier.pages3 pages
dc.identifier.urihttps://doi.org/10.2312/evp.20221116
dc.identifier.urihttps://diglib.eg.org:443/handle/10.2312/evp20221116
dc.publisherThe Eurographics Associationen_US
dc.rightsAttribution 4.0 International License
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCCS Concepts: Human-centered computing --> Visualization toolkits; Graph drawings
dc.subjectHuman centered computing
dc.subjectVisualization toolkits
dc.subjectGraph drawings
dc.titleMOBS - Multi-Omics Brush for Subgraph Visualisationen_US
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