Robust Cardiac Function Assessment in 4D PC‐MRI Data of the Aorta and Pulmonary Artery

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dc.contributor.authorKöhler, Benjaminen_US
dc.contributor.authorPreim, Utaen_US
dc.contributor.authorGrothoff, Matthiasen_US
dc.contributor.authorGutberlet, Matthiasen_US
dc.contributor.authorFischbach, Katharinaen_US
dc.contributor.authorPreim, Bernharden_US
dc.contributor.editorChen, Min and Zhang, Hao (Richard)en_US
dc.date.accessioned2016-03-01T14:13:08Z
dc.date.available2016-03-01T14:13:08Z
dc.date.issued2016en_US
dc.description.abstractFour‐dimensional phase‐contrast magnetic resonance imaging (4D PC‐MRI) allows the non‐invasive acquisition of time‐resolved, 3D blood flow information. Stroke volumes (SVs) and regurgitation fractions (RFs) are two of the main measures to assess the cardiac function and severity of valvular pathologies. The flow rates in forward and backward direction through a plane above the aortic or pulmonary valve are required for their quantification. Unfortunately, the calculations are highly sensitive towards the plane's angulation since orthogonally passing flow is considered. This often leads to physiologically implausible results. In this work, a robust quantification method is introduced to overcome this problem. Collaborating radiologists and cardiologists were carefully observed while estimating SVs and RFs in various healthy volunteer and patient 4D PC‐MRI data sets with conventional quantification methods, that is, using a single plane above the valve that is freely movable along the centerline. By default it is aligned perpendicular to the vessel's centerline, but free angulation (rotation) is possible. This facilitated the automation of their approach which, in turn, allows to derive statistical information about the plane angulation sensitivity. Moreover, the experts expect a continuous decrease of the blood flow volume along the vessel course. Conventional methods are often unable to produce this behaviour. Thus, we present a procedure to fit a monotonous function that ensures such physiologically plausible results. In addition, this technique was adapted for the usage in branching vessels such as the pulmonary artery. The performed informal evaluation shows the capability of our method to support diagnosis; a parameter evaluation confirms the robustness. Vortex flow was identified as one of the main causes for quantification uncertainties.Four‐dimensional phase‐contrast magnetic resonance imaging (4D PC‐MRI) allows the non‐invasive acquisition of time‐resolved, 3D blood flow information. Stroke volumes (SVs) and regurgitation fractions (RFs) are two of the main measures to assess the cardiac function and severity of valvular pathologies. The flow rates in forward and backward direction through a plane above the aortic or pulmonary valve are required for their quantification. Unfortunately, the calculations are highly sensitive towards the plane's angulation since orthogonally passing flow is considered.en_US
dc.description.number1en_US
dc.description.sectionheadersArticlesen_US
dc.description.seriesinformationComputer Graphics Forumen_US
dc.description.volume35en_US
dc.identifier.doi10.1111/cgf.12669en_US
dc.identifier.urihttps://doi.org/10.1111/cgf.12669en_US
dc.identifier.urihttps://diglib.eg.org:443/handle/10
dc.publisherCopyright © 2016 The Eurographics Association and John Wiley & Sons Ltd.en_US
dc.subjectscientific visualizationen_US
dc.subject4d pc‐mrien_US
dc.subjectstroke volumeen_US
dc.subjectquantificationen_US
dc.subjectI.4.9 [Computing Methodologies]: Image Processing and Computer Vision Applicationsen_US
dc.titleRobust Cardiac Function Assessment in 4D PC‐MRI Data of the Aorta and Pulmonary Arteryen_US
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