VCBM 18: Eurographics Workshop on Visual Computing for Biology and Medicine

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https://diglib.eg.org/handle/10.2312/2632660

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Browsing VCBM 18: Eurographics Workshop on Visual Computing for Biology and Medicine by Subject "Human centered computing"

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    Visual Exploratory Analysis for Multiple T-Maze Studies
    (The Eurographics Association, 2018) Bechtold, Fabrizia; Splechtna, Rainer; Matkovic, Kresimir; Puig Puig, Anna and Schultz, Thomas and Vilanova, Anna and Hotz, Ingrid and Kozlikova, Barbora and Vázquez, Pere-Pau
    Evaluation of spatial learning and memory in rodents is commonly carried out using different maze settings such as the Multiple T-Maze. State-of-the-art analysis is primarily based on statistics of quantitative measures stemming from animal trajectories in a maze, e.g. path length or correct decisions made. Currently trajectories themselves are analyzed and evaluated one at a time and comparison of multiple trajectories is a tedious task. The resulting findings may not fully answer complex questions that behavioral researchers encounter as well, e.g., why do animals behave in a certain way or can atypical behaviour be detected? This paper describes an innovative approach on how exploratory analysis for Multiple T-Maze studies can be enhanced through interactive visual analysis. We explain our solution for analyzing a whole ensemble of data at once and support the finding of orientational characteristics and migration patterns within the ensemble. We also abstract the analysis tasks for Multiple TMaze studies and, based on these tasks, we extend a coordinated multiple views system to support the solving of fundamental problems which behavioral researchers face. Besides views of standard charts we deploy a multi-resolution heat map and the Gate-O-Gon, which is a novel visual element. It gives clues on the animals' general movement orientation and distribution of revisited gates, as well as enhances the discovery of patterns in movement and identifying of irregular behavior. Finally we demonstrate the usefulness of the newly proposed approach using a real life data set consisting of 400 Multiple T-Maze runs.
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    VisualFlatter - Visual Analysis of Distortions in the Projection of Biomedical Structures
    (The Eurographics Association, 2018) Grossmann, Nicolas; Köppel, Thomas; Gröller, Eduard; Raidou, Renata Georgia; Puig Puig, Anna and Schultz, Thomas and Vilanova, Anna and Hotz, Ingrid and Kozlikova, Barbora and Vázquez, Pere-Pau
    Projections of complex anatomical or biological structures from 3D to 2D are often used by visualization and domain experts to facilitate inspection and understanding. Representing complex structures, such as organs or molecules, in a simpler 2D way often requires less interaction, while enabling comparability. However, the most commonly employed projection methods introduce size or shape distortions, in the resulting 2D representations. While simple projections display known distortion patterns, more complex projection algorithms are not easily predictable.We propose the VisualFlatter, a visual analysis tool that enables visualization and domain experts to explore and analyze projection-induced distortions, in a structured way. Our tool provides a way to identify projected regions with semantically relevant distortions and allows users to comparatively analyze distortion outcomes, either from alternative projection methods or due to different setups through the projection pipeline. The user is given the ability to improve the initial projection configuration, after comparing different setups. We demonstrate the functionality of our tool using four scenarios of 3D to 2D projections, conducted with the help of domain or visualization experts working on different application fields. We also performed a wider evaluation with 13 participants, familiar with projections, to assess the usability and functionality of the Visual Flatter.